Sharipov R.A. 1
Latуpov A.M. 2
Mironov P.I. 3
1 Bashkortostan State Medical University, Ufa
2 Republical clinical hospital, Ufa
3 Republical clinical hospital, Ufa
The aim of the study was to estimate the interrelation between the type of a parenteral nutrition and a current of the system inflammatory response at patients with cancer of a bladder after a radical cystectomy with ileocystoplasty. Design of investigation was prospective, controlled, randomized unicentral research. 27 patients were included in the study. Criteria of inclusion were age more than 18 years old, a cancer of bladder T2-T4, carrying out a radical cystectomy with ileocystoplasty according to Shtuder. Final points: dynamics of clinical signs of SSVO, level of S-jet protein, pro-inflammatory cytokines (factor of a necrosis of a tumor , and interleykina-6), pro-calcitonin. 17 patients (the main group) received the parenteral nutrition with «Nutrifleks» 48/150 lipid. 10 patients (control group) received the parenteral nutrition with glucoso-salt solutions and solution of amino acids of Aminoplazmal of 10 %. The postoperative period was accompanied by growth of levels of S-jet protein and pro-inflammatory cytokines. No intergroup distinctions in their contents was noted. As in control, and the main group almost equal number of patients with the maintenance of pro-calcitonin more than 0,5 ¡ú/ml was noted. Authors revealed that balanced parenteral nutrition in the early postoperative period promotes the reduction of duration of the system inflammatory response after a radical cystectomy with the ileocystoplasty.
system inflammatory response
nutritive support
radical cyctectomy
ileocystoplasty
cytokines
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Рецензенты:
Грицан А.И., д.м.н., профессор, зав. кафедрой анестезиологии и реаниматологии ИПО Красноярского государственного медицинского университета, г. Красноярск;
Рудакова Э.А., д.м.н., профессор, зав. кафедрой хирургических болезней детского возраста Пермской государственной медицинской академии, г. Пермь.
