Scientific journal
Fundamental research
ISSN 1812-7339
"Перечень" ВАК
ИФ РИНЦ = 1,674

THE STUDY OF XENOPERICARDIAL PLATES USING PERSPECTIVES IN THE UROGYNECOLOGY (EXPERIMENTAL STUDY)

Baulina O.A. 1 Vihrev D.V. 2 Fedorova M.G. 2 Baulin A.V. 3 Baulin V.A. 1 Venediktov A.A. 4
1 Penza state postgraduate medical institute, Penza
2 Penza state university, Penza
3 ФГБОУ ВПО «Пензенский государственный университет», Пенза
4 «Kardioplant» Ltd., Penza
The authors performed experimental study of biointegration of xenopericardial plates in the urinary tract. Experiment had two parts: in vitro and in vivo. The first part was performed to study the physical and chemical preferences of the xenopericard in the urine, conditions were almost like inside the human body. Xenopericard was placed in the dark container with 5 times a day changing urine, which temperature was between 36 and 38 grades. The experiment in vivo included the study of biointegration of the xenopericard in the urinary tract to analyze the tissue reaction. The study was performed on 4 mature male «Shinshilla» rabbits. It was found, that under urinary influence the collagen structure of the pericard fully transforms and the epithelization from the mucous side occurs. Obtained good results allow the start of applying the xenopericard in urogynecological clinical practice.
xenopericardial plate
urogynecology
1. Belousov A.E. Plasticheskaya, rekonstruktivnaya i esteticheskaya khirurgiya. St. Petersburg, Medicine, 1998, p. 21.
2. Biosovmestimost. Ed. by V.I. Sevastyanov. Moscow, ITs VNII Geosistem, 1999, 368 p.
3. Gulyaev V.A. Gomoarterialnyy protez v rekonstruktivnoy khirurgii magistralnykh arteriy. Avtoref. dis. kand. med. nauk, Moscow, 1994, 19 p.
4. Gusev S.A., Scheplev P.A., Garin N.N., Borisenko G.G. Razrabotka podkhodov k otsenke implantiruemykh trehmernykh materialov dlya tkanevoy inzhenerii. Perspektivnye materialy, 2005, no. 6, pp. 49–56.
5. Ivanov S.V., Ivanov I.S., Dolzhnikov A.A., Martyntsev A.A., Tsukanov A.V., Mamedov R.A. Morfologiya tkaney pri ispolzovanii protezov iz polipropilena i politetrafolena. Annaly khirurgii, 2009, no. 3, pp. 59–64.
6. Karmadonov A.V. Primenenie modifitsirovannogo ksenoperikarda v khirurgicheskom lechenii gryzh peredney bryushnoy stenki. Avtoref. dis. kand. med. nauk, Kemerovo, 2009, 22 p.
7. Krasnopolskiy V.I., Popov A.A., Buyanova S.N. et al. Sinteticheskie materialy v khirurgii tazovogo dna. Akusherstvo i ginekologiya, 2003, no. 6, pp. 6–8.
8. Operativnaya urologiya klassika i novatsii. L.G. Managadze, N.A. Lopatkin, O.B. Loran et al. Moscow, Madicine, 2003, pp.
9. Ratner G.L., Sidelman K.N. Tkanevaya reaktsiya na implantatsiyu nekotorikh sinteticheskikh materialov. Experimentalnaya khirurgiya i anesteziologiya, 1963, no. 3, pp. 57–58.
10. Shtilman M.I. Polimery mediko-biologicheskogo naznacheniya. Moscow, IKTs «Akademkniga», 2006, 400 p.
11. Dawson C. Urological trauma and bladder reconstruction / C. Dawson, H. Whitfield // BMJ. 2006. 312: 1352–4.
12. Kaene D.P., Sims T.J., Abrams P. et al. Analysis of collagen status in premenopausal nulliparous women with genuine stress incontinence // Obstet Gynecol. 1997. 104 (9): 994–8.
13. Sternberg K., Selent C., Hakansson N., Toollner J., Langer T., Seiter H., Shcmitz K.P. Bioartificial materials in Urology // Urologe A. 2004 Oct; 43 (10): 1 200–7.

Рецензенты:

Черепанин А.И., д.м.н., профессор кафедры госпитальной хирургии № 1 Лечебного факультета ГБОУ ВПО «Первый Московский медицинский университет им. И.М. Сеченова», г. Москва;

Смолькина А.В., д.м.н., профессор кафедры госпитальной хирургии медицинского факультета им. Т.З. Биктимирова ФГБО ВПО «Ульяновский государственный университет», г. Ульяновск.

Работа поступила в редакцию 09.10.2012.